ESSENTIAL FUNCTIONS

Primary duties/responsibilities:

• Under general guidance, executes experiments and communicates results as part of multi-disciplinary team(s).
• Applies relevant scientific principles and techniques to research problems.
• Maintains detailed laboratory notebooks.
• Maintains knowledge of state-of-the-art principles and techniques.
• Ability to trouble shoot experiments -designing controls, generating interpretable data
• Presents findings internally and contributes to the publication of the work of the project team
• Contributes to the development of patent applications as appropriate.
• Complies with all safety requirements.
• Contributes to laboratory needs, such as stock room maintenance and ordering supplies
• Involved in general lab duties as assigned.
• Specific duties may also include, but may not be limited to, the following:
• Executes weekly cell-based screening assays to support hit to lead optimization efforts for early-stage discovery programs.
• Maintains cell lines (thawing, passaging, seating) to support in vitro screening assays.
• Routinely uploads and reports data in a timely fashion which may also include communicating any delays or changes in workflow to a cross disciplinary team.
• Provides support for the design and optimization of new assays, the goal of which is the identification of additional hits.
• Profiles selected compounds to better understand compound mechanism of action in additional cells and tissues.
• Perform maintenance and run quality control tests on relevant instrumentation.

KNOWLEDGE/SKILLS/ABILITIES REQUIRED

• Tissue culture experience with excellent sterile technique required
• Knowledge of basic Cell biology and Molecular biology
• Exceptional attention to detail and time management skills
• Multicolor flow cytometry experimental design, execution, and analysis required
• Experience with automated instrumentation (for example, liquid dispensers and plate washers)

* Minimum level of education and years of relevant work experience.

• Bachelor's degree in a Biology scientific discipline, preferably Biology or Neuroscience with a minimum of 3 years' experience, OR, Master's degree in a scientific discipline with a minimum of 1 year of relevant experience.

* Special knowledge or skills needed and/or licenses or certificates required.

• Demonstrates technical proficiency, and the ability to collaborate with others on cross functional teams in a fast-paced, matrixed, environment consisting of internal and external team members.
• Possesses knowledge of scientific principles and concepts and keeps current with relevant scientific literature
• Proficiency with Microsoft Office- preferably MS Excel and MS PowerPoint.
• Effective verbal and written communication and skills.
• Analytical thinker with problem-solving skills and the ability to adapt to changing priorities and deadlines.
• Effective planning, organization and time management skills including the ability to support and prioritize multiple projects.

* Travel requirements

• Up to 5%