POSITION OBJECTIVE

Working under moderate supervision, perform research work in the biomedical field. The research lab develops nanotechnology tools to better understand cardiometabolic and neurological diseases such as atherosclerosis, type 2 diabetes, Alzheimer's disease, and traumatic brain injury.

The Research Assistant will assist and support scientists in the lab and perform standard molecular techniques (PCR, electrophoresis, RNA extraction), tissue-culturing /cell culture work, animal work, tissue processing (immunohistochemistry) and general lab maintenance. The research assistant will also collect, verify, record, and compile data and information related to the ongoing research carried out in the lab. This position will work with animals.

ESSENTIAL FUNCTIONS

1. Conduct analysis of samples (histological analysis, cell-based and biochemical assay analysis). Perform research work in medical and related technical areas involving the use of lab/ research skills with lab members by performing procedures and operating a variety of instruments and scientific equipment, i.e. microscopy, PCR, gel electrophoresis, biochemical assays, and others. (20%)
2. Maintain animal colonies and assist with procedures such as diet manipulation, drug administration, organ isolation, taking care of animals and general maintenance. (15%)
3. Collect and organize data, keep records using electronic lab notebook. Maintain records of experiments. Organize raw data and update lab-related data folders. (20%)
4. Maintain cell/ tissue cultures for experimental purposes (20%)
5. Maintain test equipment utilized in experiments. This includes using and maintaining fluorescence microscope, plate reader, PCR equipment. Maintain chemical/biological inventory in compliance with EHS, and order laboratory supplies if needed. Configure and operate laboratory instruments; ensure instruments are kept in working order. (20%)

NONESSENTIAL FUNCTIONS

Perform other duties as assigned, including laboratory waste management, communication with technical support if issues with existing lab equipment arise. (5%)

CONTACTS

Department: Continuous contact with supervisor to discuss research and maintain workflow.

University: Infrequent contact with other departments to share information.

External: Infrequent or no contact with vendors to exchange information.

Students: Regular contact with student employees to exchange information.

SUPERVISORY RESPONSIBILITY

This position has no direct supervision of staff employees.

QUALIFICATIONS

Education/Experience: Bachelor's degree in science and 0 to 1 year of experience or Associate's degree in an approved biotechnology program and 0 to 2 years of experience required.

REQUIRED SKILLS

1. Has knowledge of commonly used concepts, practices, and procedures within a molecular biology field (PCR, RNA Isolation).
2. Relies on instructions and pre-established guidelines to perform the functions of the job.
3. Ability to operate laboratory equipment. Computer skills and ability to quickly learn software, databases, online applications (Google and Amazon services).
4. Ability to meet consistent attendance.
5. Ability to stay organized.
6. Ability to train others within their own area of expertise.
7. Ability to interact with colleagues, supervisors and customers face to face.
8. Must demonstrate compliance with CWRU animal research and care (ARC) policies and procedures and compliance to regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines and other applicable regulatory guidelines.
9. Must demonstrate compassion for animals within CWRU facilities and dedication to the Animal Resource Center's mission. Must handle animals with care and respect at all times.
10. Previous experience working with animals preferred.
11. Must be able and willing to maintain a high standard of personal cleanliness and utilize protective gear to protect the health of the animals.
12. Must be able and willing to learn new techniques, procedures, processes, and computer gear to protect the health of the animals.

WORKING CONDITIONS

General laboratory environment. The laboratory is an open floor plan with abundant bench space for experiments. Ample desk space with computers is also provided. Expected to be conscientious of hazards of different chemicals used as well as animal samples. Required personal protective equipment includes a laboratory coat, gloves suitable for the types of organisms, chemicals and reagents handled and protective eyewear as appropriate. Ergonomic concerns include regular and repetitive use of keyboards and pipettes.

Case Western Reserve University's animal facilities are accredited by the Association for the Assessment and Accreditation of Laboratory Animal Care (AAALAC) and is managed according to the "Guide for the Care and Use of Laboratory Animals" appropriate Federal Animal Welfare Regulations, and the Public Health Service "Policy on the Humane Care and Use of Laboratory Animals." This position, and all animal research personnel, are subject to internal compliance to medical school Animal Resource Center Standard Operating Procedures and to compliance regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines, the State of Ohio Veterinary Practice Act, Federal Drug Enforcement Administration regulatory guidelines, US Food and Drug Administration Center for Veterinary Medicine regulations and other applicable regulatory guidelines.

In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.

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Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Equity at 216-368-3066 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.

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